HORDB

General Information

ID: hor002474
Uniprot ID: NA
Protein name: Antho-RWamide II
Gene name: NA
Organism: Calliactis parasitica
Family: NA
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: NA
GO MF: NA
GO BP: NA
GO CC: NA

Sequence Information

Sequence: EGLRW
Length: 5
Propeptide: NA
Signal peptide: NA
Modification: T5 Tryptophan amide
Glycosylation: NA
Mutagenesis: NA

Activity

Function: Evoked contractions of body wall muscles
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
Kd: NA
Half life: NA

Structure

Disulfide bond: NA
Structure ID: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor002474_AF2.pdb

hor002474_ESM.pdb

Physical Information

Mass:	73127	Formula:	C30H45N9O8
Absent amino acids:	ACDFHIKMNPQSTVY	Common amino acids:	EGLRW
pI:	6.41	Basic residues:	1
Polar residues:	1	Hydrophobic residues:	2
Hydrophobicity:	-110	Boman Index:	-1354
Half-Life / Aliphatic Index:	1 hour	Aliphatic Index:	78
Instability Index:	16108	Extinction Coefficient cystines:	5500
Absorbance 280nm:	1375

Literature

PubMed ID: 1675657
Title: Effects of Three Anthozoan Neuropeptides, Antho-RWamide I, Antho-RWamide II and Antho-RFamide, on Slow Muscles From Sea Anemones